NVS-CRF38 |
| رقم الكتالوجGC36787 |
NVS-CRF38 هو مضاد جديد لمستقبلات عامل إطلاق الكورتيكوتروبين 1 (CRF1) مع قابلية منخفضة للذوبان في الماء
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1207258-55-6
Sample solution is provided at 25 µL, 10mM.
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NVS-CRF38 is a novel corticotropin-releasing factor receptor 1 (CRF1) antagonist with low water solubility.IC50 value: Target: CRF1 antagonist
[1]. Stringer RA, et al. Preclinical metabolism and pharmacokinetics of NVS-CRF38, a potent and orally bioavailable corticotropin-releasing factor receptor 1 antagonist. Xenobiotica. 2014 Apr 3. [2]. Stringer RA, et al. 1-Aminobenzotriazole modulates oral drug pharmacokinetics through cytochrome P450 inhibition and delay of gastric emptying in rats. Drug Metab Dispos. 2014 Jul;42(7):1117-24.
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