الصفحة الرئيسية>>Signaling Pathways>> Metabolism>> Factor Xa>>Ozagrel sodium

Ozagrel sodium

رقم الكتالوجGC36831

Ozagrel sodium (OKY-046 sodium) هو أحد مثبطات سينثيز ثرومبوكسان A2 (TXA2)

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Ozagrel sodium التركيب الكيميائي

Cas No.: 189224-26-8

الحجم السعر المخزون الكميّة
5mg
35٫00
متوفر
10mM (in 1mL Water)
39٫00
متوفر
50mg
131٫00
متوفر
100mg
198٫00
متوفر

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Sample solution is provided at 25 µL, 10mM.

Description of Ozagrel sodium

Ozagrel sodium (OKY-046 sodium) is an antiplatelet agent working as a thromboxane A2 synthesis inhibitor. Thromboxane A2 Synthase

[1]. Nakazawa, M., et al., [Research and development of ozagrel, a highly selective inhibitor of TXA2 synthase]. Yakugaku Zasshi, 1994. 114(12): p. 911-33. [2]. Li, S.B., et al., In vitro effect of ozagrel on mushroom tyrosinase. Protein J, 2009. 28(3-4): p. 182-8. [3]. Westphal, M., et al., Selective thromboxane A2 synthase inhibition by OKY-046 prevents cardiopulmonary dysfunction after ovine smoke inhalation injury. Anesthesiology, 2005. 102(5): p. 954-61.

Chemical Properties of Ozagrel sodium

Cas No. 189224-26-8 SDF
Canonical SMILES O=C([O-])/C=C/C1=CC=C(CN2C=CN=C2)C=C1.[Na+]
Formula C13H11N2NaO2 M.Wt 250.23
الذوبان Water: ≥ 44 mg/mL (175.84 mM) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Ozagrel sodium

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 3.9963 mL 19.9816 mL 39.9632 mL
5 mM 0.7993 mL 3.9963 mL 7.9926 mL
10 mM 0.3996 mL 1.9982 mL 3.9963 mL
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In vivo Formulation Calculator (Clear solution) of Ozagrel sodium

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Average Rating: 5 ★★★★★ (Based on Reviews and 14 reference(s) in Google Scholar.)

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