SHR1653 |
| رقم الكتالوجGC37635 |
SHR1653 هو مضاد لمستقبلات الأوكسيتوسين (OTR) شديد الفاعلية والانتقائية واختراق الدماغ ، مع IC50 من 15 نانومتر لـ hOTR
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Cas No.: 2231770-73-1
Sample solution is provided at 25 µL, 10mM.
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SHR1653 is a highly potent, selective and brain penetrated oxytocin receptor (OTR) antagonist, with an IC50 of 15 nM for hOTR[1]. IC50: 15 nM (hOTR)[1].
[1]. Li X, et al. Discovery of SHR1653, a Highly Potent and Selective OTR Antagonist with Improved Blood-Brain Barrier Penetration. ACS Med Chem Lett. 2019 May 29;10(6):996-1001.
Average Rating: 5 (Based on Reviews and 36 reference(s) in Google Scholar.)
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