Demethoxydeacetoxypseudolaric acid B analog |
رقم الكتالوجGC38084 |
تم تصنيع نظير حمض ديميثوكسيدي أسيتوكسيديولاريك ب (المركب 13 ب) بواسطة إجراءات فعالة من حمض Pseudolaric B. وله أنشطة قوية ضد HMEC-1 و HL-60 و A-549 و MB-MDA-468 و BEL-7402 و HCT116 و خلايا Hela مع IC50s تتراوح من 0.136 إلى 1.162 ميكرومتر
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Cas No.: 500736-17-4
Sample solution is provided at 25 µL, 10mM.
Demethoxydeacetoxypseudolaric acid B analog (Compound 13b) is semi-synthesized by efficient routines from Pseudolaric acid B. It has potent activities against HMEC-1, HL-60, A-549, MB-MDA-468, BEL-7402, HCT116, and Hela cells with IC50s ranging from 0.136 to 1.162 μM[1].
[1]. Yang SP, et al. Structural modification of an angiogenesis inhibitor discovered from traditional Chinese medicineand a structure-activity relationship study. J Med Chem. 2008 Jan 10;51(1):77-85.
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