Pomalidomide-C2-NH2 hydrochloride |
| رقم الكتالوجGC38381 |
إن هيدروكلوريد بوماليدوميد- C2-NH2 عبارة عن اتحاد مركب ليجاند رابط مركب E3 ليجيز يشتمل على ليجند cereblon القائم على بوماليدوميد ورابط مستخدم في تقنية PROTAC
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Cas No.: 2305369-00-8
Sample solution is provided at 25 µL, 10mM.
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Pomalidomide-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology.
[1]. Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.
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