PROTAC ERRα ligand 2 |
| رقم الكتالوجGC38383 |
PROTAC ERRα ؛ يجند 2 هو ناهض عكسي لمستقبلات α (ERRα) المرتبط بالإستروجين مع IC 50 من 5.67 نانومتر. PROTAC ERRα ؛ يعرض ligand 2 (IC50 \u003d 5.67 نانومتر) فاعلية محسنة بمقدار 11 ضعفًا تقريبًا من XCT790 (IC50 \u003d 61.3 نانومتر).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2306388-57-6
Sample solution is provided at 25 µL, 10mM.
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PROTAC ERRα ligand 2 is an estrogen-related receptor α (ERRα) inverse agonist with an IC50 of 5.67 nM. PROTAC ERRα ligand 2 (IC50=5.67 nM) displays a ~11-fold improved potency than XCT790 (IC50=61.3 nM)[1].
[1]. Peng L, et al. Identification of New Small-Molecule Inducers of Estrogen-related Receptor α (ERRα) Degradation. ACS Med Chem Lett. 2019 Apr 12;10(5):767-772.
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