Lidoflazine |
| رقم الكتالوجGC38537 |
Lidoflazine هو مانع تقارب عالي لقناة K + (الجين البشري المرتبط بالإيثر-أ-جو-جو)
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 3416-26-0
Sample solution is provided at 25 µL, 10mM.
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Lidoflazine is a high affinity blocker of the HERG (human ether-a-go-go-related gene) K+ channel. Lidoflazine is an antianginal calcium channel blocker that carries a significant risk of QT interval prolongation and ventricular arrhythmia[1].
Lidoflazine inhibits potently HERG current (IHERG) recorded from HEK 293 cells stably expressing wild-type HERG (IC50 of ~16 nM).
[1]. https://www.ncbi.nlm.nih.gov/pubmed/15135665
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