Gentisuric Acid |
| رقم الكتالوجGD13954 |
Gentisuric acid, a metabolite of Aspirin, is a substrate of α-amidating monooxygenase (PAM).
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Cas No.: 25351-24-0
Sample solution is provided at 25 µL, 10mM.
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Gentisuric acid, a metabolite of Aspirin, is a substrate of α-amidating monooxygenase (PAM). Gentisuric acid prevents DNA-damage by Mitomycin C [1][2].
References:
[1]. DeBlassio JL, et al. Amidation of salicyluric acid and gentisuric acid: a possible role for peptidylglycine alpha-amidating monooxygenase in the metabolism of aspirin. Arch Biochem Biophys. 2000 Nov 1;383(1):46-55.
[2]. Niikawa M, et al. Suppressive effect of post- or pre-treatment of aspirin metabolite on mitomycin C-induced genotoxicity using the somatic mutation and recombination test in Drosophila melanogaster. Biomed Pharmacother. 2007 Feb-Apr;61(2-3):113-9.
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