NSC622608 (Synonyms: NSC622608) |
رقم الكتالوجGD19194 |
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Cas No.: 2593254-90-9
Sample solution is provided at 25 µL, 10mM.
NSC622608 is a V-domain Ig suppressor of T-cell activation (VISTA) ligand with an IC50 value of 4.8 渭M.
NSC622608 disrupts VISTA-VSIG-3 interaction with an IC50 value of 9.7 卤 0.3 渭M[1].
[1]. Gabr MT, et al. Discovery and Optimization of Small-Molecule Ligands for V-Domain Ig Suppressor of T-Cell Activation (VISTA). J Am Chem Soc. 2020 Sep 23;142(38):16194-16198.
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