Urokinase from human urine |
| رقم الكتالوجGD23331 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 9039-53-6
Sample solution is provided at 25 µL, 10mM.
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Urokinase (peptidolytic) (EC 3.4.21.73) is a serine protease, an inactive form (zymogen) of the serine protease plasminogen. Activation of plasmin triggers a proteolytic cascade reaction, which in turn participates in thrombolysis or extracellular matrix degradation, implicated in vascular disease and cancer-related research.
Urokinase peptidolytic(uPA) can increase the expression of uPAR protein and mRNA levels in non-small cell lung cancer (NSCLC)[1].
[1]. Nunzia Montuori, et al. Urokinase-mediated posttranscriptional regulation of urokinase-receptor expression in non small cell lung carcinoma. Int J Cancer. 2003 Jun 20;105(3):353-60
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