ES9-17 (Synonyms: ES9-17) |
| رقم الكتالوجGF13655 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 55854-43-8
Sample solution is provided at 25 µL, 10mM.
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ES9-17 (0-100 渭M; 30 min) inhibits the uptake of the lipophilic styryl endocytic tracer dye (FM4-64), with an EC50 value of 13 渭M[1].
ES9-17 (30 渭M; 30 min) doesn鈥檛 deplete cellular ATP[1].
ES9-17 (30 渭M; 30 min) also reduces the uptake of transferrin in HeLa cells[1].
ES9-17 targets to CHC and mediates transport of materials among organelles without causing cytoplasmic acidification[1].
[1]. Dejonghe W, et al. Disruption of endocytosis through chemical inhibition of clathrin heavy chain function. Nat Chem Biol. 2019 Jun;15(6):641-649.
[2]. Huang L, et al. Progress in using chemical biology as a tool to uncover novel regulators of plant endomembrane trafficking. Curr Opin Plant Biol. 2019 Dec;52:106-113.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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