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Glucocorticoid receptor agonist-2

رقم الكتالوجGC71030

Glucocorticoid receptor agonist-2 (مركب 21) هو نابه لمستقبل القشرانيات السكرية بقيمة IC50 6.6 نانومتر.

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Glucocorticoid receptor agonist-2 التركيب الكيميائي

Cas No.: 2166378-92-1

الحجم السعر المخزون الكميّة
1 mg
306٫00
متوفر
5 mg
765٫00
متوفر

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مراجعات العميل

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Glucocorticoid receptor agonist-2 (compound 21) is an glucocorticoid receptor agonist with an IC50 value of 6.6 nM. Glucocorticoid receptor agonist-2 can be used to synthesize anti-inflammatory ADC molecules. Glucocorticoid receptor agonist-2 is an active reference of ABBV-3373.

Glucocorticoid receptor agonist-2 shows glucocorticoid receptor (GR) and progersterone receptor (PR) binding activities with IC50 values of 6.6 and 7.3 nM, respectively[1].
Glucocorticoid receptor agonist-2 shows EC50 values of 0.2 and 442 nM to glucocorticoid responsive element (GRE) reporter and mineralcorticoid receptor (MR), respectively[1].
Glucocorticoid receptor agonist-2 agonists MR with an EC50 value of 149 nM[1].

مراجعات

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