Glucosamine Cholesterol |
| رقم الكتالوجGC91162 |
مركب ليبيدي يعتمد على الجلوكوزامين
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1257309-90-2
Sample solution is provided at 25 µL, 10mM.
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Glucosamine cholesterol is a glucosamine-based lipid conjugate that has been used in the formation of lipid nanoparticles (LNPs).1 It forms a stable, ordered bilayer with the glucosamine moiety facing outward to facilitate recognition by glucose transporter 1 (GLUT1) on cells. LNPs containing glucosamine cholesterol and encapsulating ceramide induce apoptosis in poxic human A549 lung carcinoma cells and A549-derived side population cells, also known as cancer stem cells (CSCs), but not poxic mouse L-929 fibroblasts. LNPs containing glucosamine cholesterol and encapsulating paclitaxel and carboplatin reduce tumor volume and increase the number of tumor-associated cytotoxic T cells in an LL/2 murine lung carcinoma model.
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