Glutaminase C Inhibitor 11 |
| رقم الكتالوجGC91427 |
مثبط الجلوتاميناز سي 11 هو مثبط لإنزيم الجلوتاميناز سي (GAC).
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Glutaminase C inhibitor 11 is an inhibitor of glutaminase C (GAC).1 It inhibits GAC enzyme activity (EC50 = 10.64 nM) and reduces the viability of A549 non-small cell lung cancer (NSCLC) cells (IC50 = 4.025 nM). Glutaminase C inhibitor 11 (0.1 and 1 µM) reduces colony formation by, and intracellular glutamate levels in, A549 cells. In vivo, glutaminase C inhibitor 11 (100 mg/kg) reduces tumor growth in an A549 mouse xenograft model.
Review for Glutaminase C Inhibitor 11
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for Glutaminase C Inhibitor 11
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