GSK-843 (Synonyms: GSK'843) |
| رقم الكتالوجGC34606 |
GSK-843 (GSK'843) هو مثبط بروتين كيناز 3 (RIP3 أو RIPK3) يتفاعل مع مستقبلات ، والذي يربط مجال كيناز RIP3 مع IC50 من 8.6 نانومتر ، ويثبط نشاط كيناز مع IC50 من 6.5 نانومتر
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1601496-05-2
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
GSK-843 is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds RIP3 kinase domain with an IC50 of 8.6 nM, and inhibits kinase activity with an IC50 of 6.5 nM[1]. IC50: 6.5 nM (RIP3)[1]
[1]. Mandal P, et al. RIP3 induces apoptosis independent of pronecrotic kinase activity. Mol Cell. 2014 Nov 20;56(4):481-95.
Average Rating: 5 (Based on Reviews and 3 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *