GSK983 |
| رقم الكتالوجGC70468 |
GSK983 هو واسع الطيف عامل مضاد للفيروسات.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 827591-02-6
Sample solution is provided at 25 µL, 10mM.
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GSK983 (0-10000 nM; 2 h) inhibits replication of adenovirus-5 (Ad-5) in primary human fibroblasts (HFF) and polyoma virus SV40 in Vero cells with the median effect concentration (K) of 21 nM, 7.5 nM; and maximum inhibition (I max) of 99%, 88%, respectively[1].
GSK983 (0-10000 nM; 72 h) inhibits the growth of cell lines immortalized by viral infection with the median effect concentration (K) of 16, 14, 7.5 nM for IM9 (EBV), B-LCL 5/2/1 (EBV), MT4 (HTLV1) cells, respectively[1].
GSK983 (10, 100 nM; 24, 48 h) induces the expression of interferon-stimulated genes in W12, HKC cells[1].
References:
[1]. Harvey R,et al. GSK983: a novel compound with broad-spectrum antiviral activity. Antiviral Res. 2009 Apr;82(1):1-11.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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