Guanosine 5'-methylenediphosphate (sodium salt) |
رقم الكتالوجGC90808 |
مثبط لإنزيم إيكتو-5'-نوكليوتيداز.
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Sample solution is provided at 25 µL, 10mM.
Guanosine 5'-metlenediphosphate is an inhibitor of ecto-5’-nucleotidase, also known as CD73 (Ki = 410 nM for the recombinant human enzyme).1 It also induces tubulin polymerization when used at a concentration of 1 mM.2 Guanosine 5'-metlenediphosphate has been used as a precursor in the synthesis of drolysis-resistant affinity resins for the purification of mRNA cap-binding proteins such as eukaryotic translation initiation factor 4E (eIF4E).3
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