GW297361 |
رقم الكتالوجGC71250 |
GW297361 هو مثبط أوكسيندول CDK الذي يثير استجابة انتقائية للصور 85 في الخلايا.
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Cas No.: 388627-21-2
Sample solution is provided at 25 µL, 10mM.
GW297361 is an oxindole CDK inhibitor that elicits a Pho85-selective response in cells. GW297361 inhibits yeast Cdk1 and Pho85 with IC50s of 20 nM and 400 nM in vitro, respectively.
GW297361 (20 μM; 15 min) partially inhibits Cdk1 within cells[1].
References:
[1]. Kung C, et al. Selective kinase inhibition by exploiting differential pathway sensitivity. Chem Biol. 2006 Apr;13(4):399-407.
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