الصفحة الرئيسية>>Signaling Pathways>> Tyrosine Kinase>> Src>>GW297361

GW297361

رقم الكتالوجGC71250

GW297361 هو مثبط أوكسيندول CDK الذي يثير استجابة انتقائية للصور 85 في الخلايا.

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GW297361 التركيب الكيميائي

Cas No.: 388627-21-2

الحجم السعر المخزون الكميّة
1 mg
306٫00
متوفر
5 mg
765٫00
متوفر

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مراجعات العميل

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
GW297361 is an oxindole CDK inhibitor that elicits a Pho85-selective response in cells. GW297361 inhibits yeast Cdk1 and Pho85 with IC50s of 20 nM and 400 nM in vitro, respectively.

GW297361 (20 μM; 15 min) partially inhibits Cdk1 within cells[1].

References:
[1]. Kung C, et al. Selective kinase inhibition by exploiting differential pathway sensitivity. Chem Biol. 2006 Apr;13(4):399-407.

مراجعات

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