H-Ile-Pro-Pro-OH |
رقم الكتالوجGC32611 |
H-Ile-Pro-Pro-OH ، ببتيد مشتق من الحليب ، يمنع الإنزيم المحول للأنجيوتنسين (ACE) مع IC 50 من 5 ميكرومتر
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 26001-32-1
Sample solution is provided at 25 µL, 10mM.
H-Ile-Pro-Pro-OH, a milk-derived peptide[1], inhibits angiotensin-converting enzyme (ACE)[1] with an IC50 of 5 μM[2]. Antihypertensive tripeptides[1].
Vitro: Ile-Pro-Pro (IPP) increases nitric oxide (NO) production in human umbilical vein endothelial cells (HUVECs)[1].
Vivo: Ile-Pro-Pro attenuates arterial dysfunction in L-NAME-treated rats[1]Ile-Pro-Pro (IPP) decreases blood pressure in spontaneously hypertensive rats (SHR) [1].Ile-Pro-Pro (IPP) attenuates the development of atherosclerosis in apolipoprotein E-deficient (apoE(-/-)) mice[1].
[1]. Nonaka A, et al. The milk-derived peptides Val-Pro-Pro and Ile-Pro-Pro attenuate arterial dysfunction in L-NAME-treated rats. Hypertens Res. 2014 Aug;37(8):703-7. [2]. Nakamura Y, et al. Purification and characterization of angiotensin I-converting enzyme inhibitors from sour milk. J Dairy Sci. 1995 Apr;78(4):777-83.
Average Rating: 5
(Based on Reviews and 33 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *