Halofantrine hydrochloride (SKF-102886) (Synonyms: (±)-Halofantrine, SKF 102886, WR 171669) |
| رقم الكتالوجGC32377 |
هالوفانترين هيدروكلوريد (SKF-102886) (SKF-102886) هو مانع لتيار البوتاسيوم المتأخر عن طريق تثبيط قناة الجينات المرتبطة بالإيثر البشري (HERG) ومركب قوي مضاد للملاريا.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 36167-63-2
Sample solution is provided at 25 µL, 10mM.
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Halofantrine hydrochloride (SKF-102886) is a blocker of delayed rectifier potassium current via the inhibition of human-ether-a-go-go-related gene (HERG) channel and a potent antimalarial compound[1][2].
[1]. Krishna S, et al. Pharmacokinetics, efficacy and toxicity of parenteral halofantrine in uncomplicated malaria. Br J Clin Pharmacol. 1993 Dec;36(6):585-91. [2]. Tie, H., et al., Inhibition of HERG potassium channels by the antimalarial agent halofantrine. Br. J. Pharmacol. 130, 1967-1975, (2000) Traebert.
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