Hamamelitannin |
| رقم الكتالوجGC60185 |
Hamamelitannin ، بوليفينول مستخرج من لحاء Hamamelis virginiana ، هو مثبط لاستشعار النصاب (QS)
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 469-32-9
Sample solution is provided at 25 µL, 10mM.
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Hamamelitannin, a polyphenol extracted from the bark of Hamamelis virginiana, is a quorum-sensing (QS) inhibitor. Hamamelitannin increases antibiotic susceptibility of staphylococcus aureus biofilms by affecting peptidoglycan biosynthesis and eDNA release[1][2].
Hamamelitannin displays specific cytotoxic activity against colon cancer cells[3].
[1]. Kiran MD, et al. Discovery of a quorum-sensing inhibitor of drug-resistant staphylococcal infections by structure-based virtual screening. Mol Pharmacol. 2008 May;73(5):1578-86. [2]. Cobrado L, et al. In vivo antibiofilm effect of cerium, chitosan and hamamelitannin against usual agents of catheter-related bloodstream infections. J Antimicrob Chemother. 2013 Jan;68(1):126-30. [3]. SÁnchez-Tena S, et al. Hamamelitannin displays specific cytotoxic activity against colon cancer cells. J Nat Prod. 2012 Jan 27;75(1):26-33.
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