Harmalol (Synonyms: 11-hydroxy Harmalan, Harmidol, NSC 72293)

Harmalol is an analytical reference standard categorized as a β-carboline alkaloid.¹ Harmalol is an active metabolite of harmaline .² It is a minor component of ayahuasca, a botanical mixture that has hallucinogenic properties.³ This product is intended for research and forensic applications.

1.Tarpley, M., Oladapo, H.O., Strepay, D., et al.Identification of harmine and β-carboline analogs from a high-throughput screen of an approved drug collection; profiling as differential inhibitors of DYRK1A and monoamine oxidase A and for in vitro and in vivo anti-cancer studiesEur. J. Pharm. Sci.162105821(2021) 2.Brierley, D.I., and Davidson, C.Developments in harmine pharmacology - implications for ayahuasca use and drug-dependence treatmentProg. Neuropsychopharmacol. Biol. Psychiatry39(2)263-272(2012) 3.Navickiene, S., Santos, L.F.S., Santos, M.C., et al.Use of coconut charcoal and menthone-thiosemicarbazone polymer as solid phase materials for the determination of N,N-dimethyltryptamine, harmine, harmaline, harmalol, and tetrahydroharmine in Ayahuasca beverage by liquid chromatography-tandem mass spectrometryJ. Braz. Chem. Soc.30(1)180-187(2019)