Helvolic Acid (Synonyms: BRN 3230584, Fumigacin, NSC 319943) |
| رقم الكتالوجGC43811 |
حمض الهيلفوليك (Fumigacin) هو مضاد حيوي معزول عن Xylaria sp ، فعال ضد البكتيريا موجبة الجرام
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Cas No.: 29400-42-8
Sample solution is provided at 25 µL, 10mM.
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Helvolic acid is a mycotoxin originally isolated from A. fumigatus that has broad-spectrum antibiotic activity against Gram-positive and Gram-negative bacteria. At 4-16 mg/L, it acted synergistically with erythromycin (500-2,000 mg/L) in vitro on five multi-drug resistant strains of S. aureus. At 10 mg/kg/d, it reduced tumor growth and prolonged survival synergistically with cyclophosphamide (20 mg/kg/d) in a mouse model of sarcoma but had no effect when administered alone.
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