HG-7-85-01-NH2 |
| رقم الكتالوجGC65351 |
HG-7-85-01-NH2 هو يجند SNIPER (ABL) -033
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1258391-29-5
Sample solution is provided at 25 µL, 10mM.
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HG-7-85-01-NH2 is the ligand of SNIPER(ABL)-033. SNIPER(ABL)-033, conjugating HG-7-85-01 (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 value of 0.3 μM[1].
[1]. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.
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