(-)-Hydroxycitric acid |
| رقم الكتالوجGC71452 |
(-)-Hydroxycitric acid حمض غارسينيا هو الحمض الرئيسي لقشور الفاكهة من Garcinia cambogia.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 27750-10-3
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
(-)-Hydroxycitric acid (0-50 µM) reduces lipid droplets accumulation, and decreases ATP-citrate lyase, fatty acid synthase and sterol regulatory element binding protein-1c mRNA level in primary chicken hepatocytes[4].
(-)-Hydroxycitric acid (1.0 mg/kg embryos, injection) reduces lipid droplets accumulation, triglyceride content, lipogenesis factors mRNA level and increases lipolysis factors mRNA expression in chicken embryos[3].
(-)-Hydroxycitric acid (p.o., once) shows a LD50 of greater than 5000 mg/kg in fasted male and female Albino rats[5].
(-)-Hydroxycitric acid (1000-3000 mg/kg diet for 8 weeks) reduces body weight gain, increases feed conversion ratio, and promotes protein synthesis in rats[6].
References:
[1]. B. S. Jena, et al. Chemistry and Biochemistry of (−)-Hydroxycitric Acid from Garcinia. J. Agric. Food Chem. 2002, 50, 1, 10-22.
[2]. Hayamizu K, et al. Effects of garcinia cambogia (Hydroxycitric Acid) on visceral fat accumulation: a double-blind, randomized, placebo-controlled trial. Curr Ther Res Clin Exp. 2003 Sep;64(8):551-67.
[3]. Li S, et al. (-)-Hydroxycitric Acid Influenced Fat Metabolism via Modulating of Glucose-6-phosphate Isomerase Expression in Chicken Embryos. J Agric Food Chem. 2019 Jul 3;67(26):7336-7347.
[4]. Li L, et al. (-)-Hydroxycitric Acid Reduced Lipid Droplets Accumulation Via Decreasing Acetyl-Coa Supply and Accelerating Energy Metabolism in Cultured Primary Chicken Hepatocytes. Cell Physiol Biochem. 2017;43(2):812-831.
[5]. Ohia SE, et al. Safety and mechanism of appetite suppression by a novel hydroxycitric acid extract (HCA-SX). Mol Cell Biochem. 2002 Sep;238(1-2):89-103.
[6]. Han N, et al. (-)-Hydroxycitric Acid Nourishes Protein Synthesis via Altering Metabolic Directions of Amino Acids in Male Rats. Phytother Res. 2016 Aug;30(8):1316-29.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *