IGS-1.76 |
| رقم الكتالوجGC63016 |
IGS-1.76 يثبط بكفاءة مجمع NCS-1 / Ric8a البشري.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 313480-47-6
Sample solution is provided at 25 µL, 10mM.
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IGS-1.76 efficiently inhibits the human NCS-1/Ric8a complex. IGS-1.76 shows a significantly increased affinity for hNCS-1 and is able to modulate the hNCS-1/Ric8a interaction efficiently[1].
IGS-1.76 is a Drosophila NCS-1/IGS-1.76 complex inhibitor[1].
[1]. Carlos Roca, et al. Deciphering the Inhibition of the Neuronal Calcium Sensor 1 and the Guanine Exchange Factor Ric8a with a Small Phenothiazine Molecule for the Rational Generation of Therapeutic Synapse Function Regulators. J Med Chem. 2018 Jul 26;61(14):5910-5921.
Average Rating: 5 (Based on Reviews and 37 reference(s) in Google Scholar.)
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