IMM 01 |
| رقم الكتالوجGB40241 |
Small-molecule agonist of mammalian Diaphanous (mDia)-related formins that inhibited DID-DAD binding (IC50 value 140 nM). IMM-01 induced filopodia-like structures similar to those observed in cells expressing constitutively active mDia1 or mDia2. Moreover, IMM01 triggered actin assembly and microtubule stabilization consistent with formin activation in NIH 3T3 cells.
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Cas No.: 218795-74-5
Sample solution is provided at 25 µL, 10mM.
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Small-molecule agonist of mammalian Diaphanous (mDia)-related formins that inhibited DID-DAD binding (IC50 value 140 nM). IMM-01 induced filopodia-like structures similar to those observed in cells expressing constitutively active mDia1 or mDia2. Moreover, IMM01 triggered actin assembly and microtubule stabilization consistent with formin activation in NIH 3T3 cells.
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