Indazole-Cl |
| رقم الكتالوجGC70778 |
Indazole-Cl (Ind-Cl) هو مستقبلات الاستروجين (ER)-β-specific agonist مع تأثير التهابي.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 848142-62-1
Sample solution is provided at 25 µL, 10mM.
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Indazole-Cl (0.1 μM; 6 h) decreases intracellular ROS levels induced by hypoxia in vascular smooth muscle cells (VSMCs)[1].
Indazole-Cl (10 μM; 24 h) inhibits hypoxia-induced cyclooxygenase (COX)-2 transcriptional activity in VSMCs[1].
Indazole-Cl (1 μM; 24-72 h) prevents hypoxia-induced cellular migration and invasion in VSMCs[1].
References:
[1]. Park C, et al. Indazole-Cl inhibits hypoxia-induced cyclooxygenase-2 expression in vascular smooth muscle cells. J Mol Endocrinol. 2019 Jul 1;63(1):27-38.
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