InhA-IN-2 |
| رقم الكتالوجGC70980 |
InhA-IN-2 (المركب 23) هو مثبط إنها السل المتفطرة (إينويل ACP-reductase) مع IC50 من 0.31 ميكرومتر.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2428737-43-1
Sample solution is provided at 25 µL, 10mM.
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InhA-IN-2 (Compound 23) is a Mycobacterium tuberculosis InhA (an enoyl ACP-reductase) inhibitor with an IC50 of 0.31 μM.
InhA-IN-2 (Compound 23) (200 µM, 48h) inhibits mycolic acid synthesis (33% growth inhibition) in M. tuberculosis H37Ra[1].
References:
[1]. Sabbah M, et al. Fragment-Based Design of Mycobacterium tuberculosis InhA Inhibitors. J Med Chem. 2020 May 14;63(9):4749-4761.
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