IRF5-IN-1 |
| رقم الكتالوجGC71096 |
IRF5-IN-1 (المركب C5) هو مثبط محدد لمسار IRF5.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 689270-18-6
Sample solution is provided at 25 µL, 10mM.
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IRF5-IN-1 (compound C5) is an IRF5 pathway-specific inhibitor. IRF5-IN-1 significantly reduces IRF5 nuclear translocation without affecting the activation of NF-κB p65. IRF5-IN-1 acts through SLC15A4 to selectively inhibit TLR7/8-induced IRF5 responses in cells.
References:
[1]. Andras Boeszoermenyi, et al. A conformation-locking inhibitor of SLC15A4 with TASL proteostatic anti-inflammatory activity. Nat Commun. 2023 Oct 20;14(1):6626.
Review for IRF5-IN-1
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for IRF5-IN-1
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