الصفحة الرئيسية>>Signaling Pathways>> Others>>Itch-Targeting Compound 1

Itch-Targeting Compound 1

رقم الكتالوجGC32024

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Itch-Targeting Compound 1 التركيب الكيميائي

Cas No.: 793674-76-7

الحجم السعر المخزون الكميّة
1mg
1232٫00
متوفر
5mg
2464٫00
متوفر
10mg
4220٫00
متوفر
20mg
7427٫00
متوفر

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مراجعات العميل

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Sample solution is provided at 25 µL, 10mM.

Description of Itch-Targeting Compound 1

Itch-Targeting Compound 1 is an anti-itching agent.

Anti-itching Compound 1 (Example 6-4) is effective in preventing itches and is useful for the prevention of or treatments for: reactions on insect's bites, reactions on environmental allergens, skin infections, external vermination, or itches occurring in renal dialysis patients[1].

[1]. MURAKI, Yukiko. 4-(2-FUROYL)AMINOPIPERIDINE COMPOUND USEFUL AS THERAPEUTIC AGENT FOR ITCHING. WO 2004099194 A1.

Chemical Properties of Itch-Targeting Compound 1

Cas No. 793674-76-7 SDF
Canonical SMILES O=C(C1=CC=CO1)N(C2CCN(CCC(C3CCCCC3)O)CC2)C4=NC=C(C)C=C4.[H]Cl
Formula C25H36ClN3O3 M.Wt 462.02
الذوبان Soluble in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Itch-Targeting Compound 1

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.1644 mL 10.822 mL 21.6441 mL
5 mM 0.4329 mL 2.1644 mL 4.3288 mL
10 mM 0.2164 mL 1.0822 mL 2.1644 mL
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** عند إعداد حلول المخزون، دائمًا استخدم الوزن الجزيئي الخاص بالدفعة للمنتج على ملصق القارورة MSDS / CoA (متوفر عبر الإنترنت).

احسب

In vivo Formulation Calculator (Clear solution) of Itch-Targeting Compound 1

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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مراجعات

Review for Itch-Targeting Compound 1

Average Rating: 5 ★★★★★ (Based on Reviews and 31 reference(s) in Google Scholar.)

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