Lipid U-101 |
| رقم الكتالوجGC91814 |
Lipid U-101 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo.
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Sample solution is provided at 25 µL, 10mM.
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Lipid U-101 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo.[1] LNPs containing lipid U-101 and encapsulating mRNA encoding a fusion protein composed of IL-2, a linker, and CD25 inhibit tumor growth in an MC-38 mouse xenograft model.
References:
[1].Jiang, Y., Zhang, Y., Liu, C., et al.Tumor-activated IL-2 mRNA delivered by lipid nanoparticles for cancer immunotherapyJ. Control. Release368663-675(2024).
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