Lipoamido-PEG3-OH |
رقم الكتالوجGC67162 |
Lipoamido-PEG3-OH عبارة عن رابط PROTAC قائم على PEG يمكن استخدامه في تخليق PROTACs. يمكن استخدام Lipoamido-PEG3-OH (مركب TA-TEG-G2CN) في تكوين منصة توصيل أدوية تعتمد على جزيئات الذهب النانوية المستقرة للغاية (AuNP).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1342764-64-0
Sample solution is provided at 25 µL, 10mM.
Lipoamido-PEG3-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Lipoamido-PEG3-OH (compound TA-TEG-G2CN) can be used in the formation of a highly stable, dendronized gold nanoparticle (AuNP)-based drug delivery platform[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. Saha Ray A,et al. Set of Highly Stable Amine- and Carboxylate-Terminated Dendronized Au Nanoparticles with Dense Coating and Nontoxic Mixed-Dendronized Form.Langmuir. 2019 Mar 5;35(9):3391-3403.
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