LU-005i |
رقم الكتالوجGC71046 |
يعتبر LU-005i مثبط قوي لوحدة بيتا 5i الفرعية من البروتيازومات المناعية (IC50 = 6.6 نانومتر)، انتقائي على وحدة بيتا 5c الفرعية (IC50 = 287 نانومتر).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1620107-33-6
Sample solution is provided at 25 µL, 10mM.
LU-005i is a potent inhibitor of β5i subunit of immunoproteasomes (IC50 = 6.6 nM), selective over β5c subunit (IC50 = 287 nM).
References:
[1]. Rezvan Moallemian, et al. Immunoproteasome inhibitor DPLG3 attenuates experimental colitis by restraining NF-κB activation.Biochem Pharmacol. 2020 Jul:177:113964.
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