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Lubeluzole

رقم الكتالوجGC70244

Lubeluzole هو مركب عصبي مضاد للإقفار

Products are for research use only. Not for human use. We do not sell to patients.

Lubeluzole التركيب الكيميائي

Cas No.: 144665-07-6

الحجم السعر المخزون الكميّة
5 mg
288٫00
متوفر

Tel:(909) 407-4943 Email: sales@glpbio.com

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Lubeluzole is a neuroprotective anti-ischemic compound. Lubeluzole, but not its (-)-R-isomer, protects against sensorimotor deficits provoked by photochemical stroke in rats. Lubeluzole inhibited glutamate-stimulated guanosine 3',5'-cyclic monophosphate production with an IC50 of 37 nM. Lubeluzole also has the potential for developing a novel class of antibacterial adjuvants endowed with spasmolytic activity.

References:
[1]. Cavalluzzi MM, et al. Lubeluzole: from anti-ischemic drug to preclinical antidiarrheal studies. Pharmacol Rep. 2021;73(1):172-184.
[2]. Lesage AS, et al. Lubeluzole, a novel long-term neuroprotectant, inhibits the glutamate-activated nitric oxide synthase pathway. J Pharmacol Exp Ther. 1996;279(2):759-766.
[3]. Cavalluzzi MM, Budriesi R, De Salvia MA, et al. Lubeluzole: from anti-ischemic drug to preclinical antidiarrheal studies. Pharmacol Rep. 2021;73(1):172-184.

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