الصفحة الرئيسية>>Signaling Pathways>> Antibody-drug Conjugate/ADC Related>> Drug-Linker Conjugates for ADC>>Lys-SMCC-DM1 (Lys-Nε-MCC-DM1)

Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) (Synonyms: Lys-Nε-MCC-DM1)

رقم الكتالوجGC33500

Lys-SMCC-DM1 (Lys-N&epsilon ؛ -MCC-DM1) (Lys-Nε ؛ -MCC-DM1) هو مكون حمولة رابط لديه القدرة على تثبيط بلمرة توبولين. -MCC-DM1) هو المستقلب النشط لـ T-DM1. T-DM1 هو مستقبل عامل نمو البشرة البشري 2 (HER2) - يستهدف ADC بمانع بلمرة توبولين DM1.

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Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) التركيب الكيميائي

Cas No.: 1281816-04-3

الحجم السعر المخزون الكميّة
10mM (in 1mL DMSO)
1618٫00
متوفر
1mg
321٫00
متوفر
5mg
873٫00
متوفر
10mg
1333٫00
متوفر

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مراجعات العميل

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  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Lys-SMCC-DM1 is the active metabolite of T-DM1. T-DM1 is an FDA approved HER2-targeting ADC.

[1]. Ogitani Y, et al. Bystander killing effect of DS-8201a, a novel anti-human epidermal growth factor receptor 2 antibody-drug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity. Cancer Sci. 2016 Jul;107(7):1039-46.

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