m-PEG7-CH2-OH |
رقم الكتالوجGC67321 |
يمكن استخدام رابط PROTAC المستند إلى PEG-CH2-OH m-PEG7-CH2-OH في تركيب PROTACs.
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Cas No.: 1807512-35-1
Sample solution is provided at 25 µL, 10mM.
m-PEG7-CH2-OH a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. KunioOka, et al. Thermochromism and solvatochromism of non-ionic polar polysilanes. Journal of Organometallic Chemistry.
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