MCHr1 antagonist 1 |
| رقم الكتالوجGC31628 |
مضاد MCHR1 1 هو مضاد انتقائي لمستقبل هرمون الميلانين 1 (MCH1) ، مع كيلو بايت من 1 نانومتر وكي 4 نانومتر عند MCH1 البشري ، ويمكن استخدامه لتقليل كتلة الجسم
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Cas No.: 391610-37-0
Sample solution is provided at 25 µL, 10mM.
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MCHr1 antagonist 1 is a selective antagonist of melanin concentrating hormone-1 (MCH1) receptor, with a Kb of 1 nM and a Ki of 4 nM at human MCH1, and may be used to reduce the body mass.
MCHr1 antagonist 1 shows potent activities against melanin concentrating hormone-1 receptor, but less potent against human MCH1, NPY1, NPY5, GALR1, GALR2, GALR3, and rat 5HT2C receptors, with Kis of >50000 nM[1].
[1]. Selective melanin concentrating hormone-1 (MCH1) receptor antagonists and uses thereof. US 20030069261 A1
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