MCL-1/BCL-2-IN-3 |
| رقم الكتالوجGC38928 |
MCL-1 / BCL-2-IN-3 (المركب 2) هو مثبط ثنائي قوي وانتقائي Mcl-1 و Bcl-2 مع IC50s من 5.95 و 4.78 ميكرومتر ، على التوالي
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Cas No.: 2163793-55-1
Sample solution is provided at 25 µL, 10mM.
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MCL-1/BCL-2-IN-3 (Compound 2) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor with IC50s of 5.95 and 4.78 μM, respectively[1].
[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.
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