Methuosis inducer 1 |
| رقم الكتالوجGC65154 |
محفز الميثوس 1 هو محفز ميثوس قوينشاط مضاد للسرطان
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2240205-30-3
Sample solution is provided at 25 µL, 10mM.
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Methuosis inducer 1 is a potent methuosis inducer[1]. Anticancer activity[1].
Methuosis inducer 1 (Compound 13) shows a broad spectrum of cytotoxicity against a panel of human cancer cell lines with IC50 values of 0.326±0.026 μM, 1.370±0.061 μM, 1.662±0.128 μM, 1.892±0.092 μM, 1.571±0.066 μM, 2.268±0.100 μM, 2.611±0.739 μM, 1.008±0.042 μM, 1.566±0.015 μM, and 1.197±0.344 μM for A375, SK-MEL-28, SK-MEL-30, A549, MDA-MB-231, MDA-MB-435S, MCF-7, HCT116, BGC823, HepG2 cells, respectively[1].
[1]. Huang W, et al. Discovery and Identification of Small Molecules as Methuosis Inducers with in Vivo Antitumor Activities. J Med Chem. 2018 Jun 28;61(12):5424-5434.
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