Misoprostol (free acid) |
| رقم الكتالوجGC41442 |
الميزوبروستول (حمض مجاني) هو مستقلب نشط من الميزوبروستول.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 112137-89-0
Sample solution is provided at 25 µL, 10mM.
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Misoprostol is a prostaglandin E1 analog with agonist activity mediated by EP2, EP3, and EP4 receptors. It has been shown to inhibit the formation of gastric lesions in rats (ED50 = 0.31 µg/kg), inhibit superoxide generation in human neutrophils (EC50 = 0.35 µM), and relax fetal rabbit ductus arteriosus (EC50 = 0.36 nM) in a concentration dependent manner. Misoprostol is commonly used in clinical medicine for the prevention of peptic ulcer disease. It has also been used in conjunction with mifepristone for the oral induction of first trimester abortion. Misoprostol contains a C-1 methyl ester and is readily absorbed and rapidly hydrolyzed in humans to the active free acid.
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