MitoP-d15 (Synonyms: MitoPhenol-d15) |
| رقم الكتالوجGC47684 |
A neuropeptide with diverse biological activities
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: N/A
Sample solution is provided at 25 µL, 10mM.
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MitoP-d15 is intended for use as an internal standard for the quantification of MitoP by GC- or LC-MS. MitoP is a phenol product produced by the reaction of H2O2 with the ratiometric mass spectrometry probe MitoB . MitoB contains a triphenylphosphonium cation component that drives its accumulation in mitochondria where its arylboronic moiety selectively reacts with H2O2 to produce MitoP.1,2 Quantifying the MitoP/MitoB ratio by LC-MS/MS reflects the mitochondrial matrix H2O2 concentration.
1.CochemÉ, H.M., Quin, C., McQuaker, S.J., et al.Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrixCell Metabolism13(3)340-350(2011) 2.CochemÉ, H.M., Logan, A., Prime, T.A., et al.Using the mitochondria-targeted ratiometric mass spectrometry probe MitoB to measure H2O2 in living DrosophilaNature Protocols7(5)946-958(2012)
Average Rating: 5 (Based on Reviews and 11 reference(s) in Google Scholar.)
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