MptpB-IN-1 |
| رقم الكتالوجGC64709 |
MptpB-IN-1 (المركب 13) هو مثبط قوي وفعال عن طريق الفم لـ MptpB
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2244622-44-2
Sample solution is provided at 25 µL, 10mM.
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MptpB-IN-1 (Compound 13) is a potent and orally active inhibitor of MptpB. Mycobacterium tuberculosis protein-tyrosine-phosphatase B (MptpB) is a secreted virulence factor that subverts antimicrobial activity in the host. MptpB-IN-1 reduces multidrug-resistant mycobacterium tuberculosis survival and infection burden[1].
[1]. Vickers CF, et al. Structure-Based Design of MptpB Inhibitors That Reduce Multidrug-Resistant Mycobacterium tuberculosis Survival and Infection Burden in Vivo. J Med Chem. 2018;61(18):8337-8352.
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