N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl) |
رقم الكتالوجGC65725 |
N- (t-Boc-Aminooxy-PEG2) -N-bis (PEG3-propargyl) عبارة عن رابط PROTAC قائم على PEG يمكن استخدامه في تركيب PROTACs.
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Cas No.: 2112737-60-5
Sample solution is provided at 25 µL, 10mM.
N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
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