N1,N12-Diacetylspermine (hydrochloride) (Synonyms: BAS) |
| رقم الكتالوجGC44283 |
N1 ، N12-Diacetylspermine (هيدروكلوريد) هو مشتق ثنائي الأسيتيل من الحيوانات المنوية. تم ربط زيادة تنظيم N1 و N12-Diacetylspermine (هيدروكلوريد) بحدوث السرطان ، مما يجعلها علامة بيولوجية محتملة للكشف عن السرطان.
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Cas No.: 77928-71-3
Sample solution is provided at 25 µL, 10mM.
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N1,N12-Acetylspermine is a diacetylated derivative of spermine , an endogenous polyamine synthesized from spermidine , that displays lower Km and higher Vmax values than spermine, making it a better substrate of polyamine oxidase than the non-acetylated polyamine. Spermine is required for eukaryotic cell growth and protein synthesis and is involved in the modulation of calcium-dependent immune processes. Upregulation of N1,N12-acetylspermine has been linked to the incidence of cancer, making this natural polyamine a potential biomarker for cancer detection.
Average Rating: 5 (Based on Reviews and 40 reference(s) in Google Scholar.)
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