الصفحة الرئيسية>>Signaling Pathways>> Proteases>> Lactate Dehydrogenase>>Nedosiran sodium

Nedosiran sodium

رقم الكتالوجGC70681

Nedosiran sodium هو مرافق GalNAc-dsRNA مصمم لمنع إنتاج إنزيم نازعة هيدروجين اللاكتات الكبدية (LDH).

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Nedosiran sodium التركيب الكيميائي

Cas No.: 2247026-22-6

الحجم السعر المخزون الكميّة
1 mg
306٫00
متوفر
5 mg
765٫00
متوفر

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مراجعات العميل

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Nedosiran sodium is a GalNAc-dsRNA conjugate designed to inhibit production of the hepatic lactate dehydrogenase (LDH) enzyme.

References:
[1]. Kevin Shee, et al. Nedosiran Dramatically Reduces Serum Oxalate in Dialysis-Dependent Primary Hyperoxaluria 1: A Compassionate Use Case Report. Urology.2021 Oct;156:e147-e149.
[2]. Gema Ariceta, et al. Hepatic Lactate Dehydrogenase A: An RNA Interference Target for the Treatment of All Known Types of Primary Hyperoxaluria. Kidney Int Rep.2021 Feb 3;6(4):1088-1098.
[3]. Thomas A Forbes, et al. Therapeutic RNA interference: A novel approach to the treatment of primary hyperoxaluria. Br J Clin Pharmacol.2021 May 22.

مراجعات

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