Nitenpyram-d3 |
| رقم الكتالوجGC47778 |
A neuropeptide with diverse biological activities
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: N/A
Sample solution is provided at 25 µL, 10mM.
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Nitenpyram-d3 is intended for use as an internal standard for the quantification of nitenpyram by GC- or LC-MS. Nitenpyram is an agonist of insect nicotinic acetylcholine receptors (nAChRs) that does not act at mammalian nAChRs.1 Nitenpyram is classified as a chloronicotinyl neonicotinoid and has high, short-term efficacy against fleas in dogs and cats when administered orally.2 Formulations containing nitenpyram have been used to control sucking insects on crops and animals.1,2
1.Tomizawa, M., and Casida, J.E.Selective toxicity of neonicotinoids attributable to specificity of insect and mammalian nicotinic receptorsAnnu. Rev. Entomol.48339-364(2003) 2.Vo, D.T., Hsu, W.H., Abu-Basha, E.A., et al.Insect nicotinic acetylcholine receptor agonists as flea adulticides in small animalsJ. Vet. Pharmacol. Ther.33(4)315-322(2010)
| Cas No. | N/A | SDF | |
| Canonical SMILES | ClC1=CC=C(CN(CC)/C(NC([2H])([2H])[2H])=C/[N+]([O-])=O)C=N1 | ||
| Formula | C11H12ClD3N4O2 | M.Wt | 273.7 |
| الذوبان | DMSO: soluble,Methanol: soluble | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 3.6536 mL | 18.2682 mL | 36.5364 mL |
| 5 mM | 0.7307 mL | 3.6536 mL | 7.3073 mL |
| 10 mM | 0.3654 mL | 1.8268 mL | 3.6536 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >99.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 16 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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