NLS-StAx-h |
رقم الكتالوجGC50489 |
NLS-StAx-h هو مثبط انتقائي للببتيد مدبب لإشارة Wnt مع IC 50 من 1.4 ميكرومتريمنع NLS-StAx-h بكفاءة تفاعلات عامل النسخ β-cateninيمنع NLS-StAx-h تكاثر وهجرة خلايا سرطان القولون والمستقيم
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Cas No.: 2872559-21-0
Sample solution is provided at 25 µL, 10mM.
Wnt inhibitor (IC50 = 1.4 μM). Stapled peptide inhibitor of oncogenic Wnt signaling. Inhibits β-catenin-transcription factor interactions. Inhibits proliferation and migration of colorectal cancer cells. Cell permeable.
Dietrich et al (2017) Cell permeable stapled peptide inhibitor of Wnt signaling that targets beta -catenin protein-protein Interactions. Cell Chem.Biol. 24 958 PMID:28757184
Average Rating: 5
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