الصفحة الرئيسية>>Signaling Pathways>> Chromatin/Epigenetics>> Histone Acetyltransferases>>NSC 694621

NSC 694621

رقم الكتالوجGC66049

NSC 694621 هو مثبط قوي لـ PCAF ، مع IC50 من 5.71 μ ؛ M (PCAF / H31-21). يُظهر NSC 694621 نشاطًا جيدًا في منع تكاثر الخلايا السرطانية.

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NSC 694621 التركيب الكيميائي

Cas No.: 104857-29-6

الحجم السعر المخزون الكميّة
10mg
144٫00
متوفر
25mg
315٫00
متوفر
50mg
495٫00
متوفر
100mg
855٫00
متوفر

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مراجعات العميل

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

IC50: 5.71 µM (PCAF/H31-21)[1].

NSC 694621 is a potent PCAF inhibitor, with an IC50 of 5.71 µM (PCAF/H31-21). NSC 694621 exhibits good activity of inhibiting the proliferation of cancer cells[1].

NSC 694621 (25 µM; 72 h) exhibits antiproliferative effect to SK-N-SH and HCT116 cells[1].

Cell Proliferation Assay[1]

Cell Line: SK-N-SH, HCT116 cells
Concentration: 25 µM
Incubation Time: 72 h
Result: Showed antiproliferative effect to SK-N-SH and HCT116 cells with GI50 of 19.2 µM and growth inhibition of 29%, respectively.

مراجعات

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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