Obtusin |
| رقم الكتالوجGC39018 |
Obtusin ، المعزول من بذور Cassia Obtusifolia Linn ، هو مثبط بشري أحادي الأمين أوكسيديز A (hMAO-A) انتقائي للغاية وتنافسي مع IC50 من 11.12 ميكرومتر و Ki 6.15 ميكرومتر
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Cas No.: 70588-05-5
Sample solution is provided at 25 µL, 10mM.
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Obtusin, isolated from Cassia obtusifolia Linn seed, is a highly selective and competitive human monoamine oxidase-A (hMAO-A) inhibitor with an IC50 of 11.12 μM and a Ki of 6.15. Obtusin plays a preventive role in neurodegenerative diseases, especially anxiety and depression[1].
[1]. Paudel P, et al. In Vitro and in Silico Human Monoamine Oxidase Inhibitory Potential of Anthraquinones, Naphthopyrones, and Naphthalenic Lactones from Cassia obtusifolia Linn Seeds. ACS Omega. 2019 Sep 18;4(14):16139-16152.
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